Semaglutide — STEP-1
Adults on semaglutide 2.4 mg weekly lost about 15% of body weight over 68 weeks; roughly a third lost 20% or more.
Free Tool · GLP-1 TherapyGLP-1 weight loss
GLP-1 weight loss
calculator.
Estimate how much weight you could lose on semaglutide (Wegovy, Ozempic) or tirzepatide (Zepbound, Mounjaro) — and roughly when. Modeled on published trial data by a board-certified internal medicine physician.
Estimated total loss
44 lbs (20%)
That would take you from 220 lbs to roughly 176 lbs at plateau, assuming you reach and tolerate a maintenance dose.
| Month | Weight lost | Weight |
|---|---|---|
| Month 1 | 3 lbs | 217 lbs |
| Month 3 | 13 lbs | 207 lbs |
| Month 6 | 27 lbs | 193 lbs |
| Month 9 | 36 lbs | 184 lbs |
| Month 12 | 41 lbs | 179 lbs |
| Month 18 | 44 lbs | 176 lbs |
Estimates only, based on trial averages — not a prediction or medical advice. Nothing you enter is stored.
Where the numbers come from
The trial data behind this tool.
Tirzepatide — SURMOUNT-1
Adults on tirzepatide 10–15 mg weekly lost roughly 20% of body weight over 72 weeks, with the highest dose performing best.
Head to head — SURMOUNT-5
Compared directly, tirzepatide outperformed semaglutide — but the medication you tolerate and stay on is the one that works.
FAQ
GLP-1 results, answered.
Usually slowly at first. The first 4–8 weeks are a starter dose meant to build tolerance, not to drive loss. Most people see the steepest change between months 3 and 9, then a gradual flattening. See our guide to GLP-1 side effects for what the first months feel like.
Tirzepatide produces more weight loss on average; semaglutide has longer real-world history and cardiovascular outcome data. We compare them in detail in Zepbound vs. Wegovy.
Protein and resistance training. A meaningful share of rapid weight loss can be lean mass if you don't defend it. Set your target with the protein calculator, and use the fiber calculator for satiety and GI comfort.
Most people regain a substantial share, because these medications manage an ongoing biological drive rather than cure it. Any taper should be deliberate and paired with a nutrition and training plan already in place.
Yes — Elios Wellness provides physician-supervised semaglutide and tirzepatide care by telemedicine across California, with labs, titration, and follow-up included in membership.
Beyond the estimate
A plan built on your labs, not trial averages.
Concierge weight-loss and metabolic care by telemedicine across California — $500 first month including your initial consultation, then $250/month.
Book a free consult